On May 5, 2025, NewLimit Raises $130M, as NewLimit, a longevity startup co-founded by Coinbase CEO Brian Armstrong, secured $130 million in a Series B funding round led by Kleiner Perkins. Valued at $810 million, the San Francisco-based company focuses on epigenetic reprogramming to develop anti-aging therapies, identifying three drug candidates for liver cell rejuvenation. With a $3.2 trillion biotech and crypto market backdrop, NewLimit Raises $130M to accelerate clinical trials. This article explores how NewLimit advances longevity research, its implications for investors, and future prospects.
Why NewLimit Raises $130M

NewLimit Raises $130M to fund its mission of extending human lifespans through epigenetic reprogramming, a technique to reverse cellular aging. Founded in 2021 by Brian Armstrong and Blake Byers, NewLimit leverages AI to identify therapies that reprogram cells, targeting age-related diseases. The Series B round, with participation from Khosla Ventures, Human Capital, Founders Fund, and angels like Patrick Collison, builds on a $40 million Series A in 2023, bringing total funding to $170 million.
Posts on X reflect optimism, with users highlighting NewLimit’s potential to revolutionize biotech, though some note the long timeline to clinical trials. NewLimit secures $130M to scale its AI-driven research, aligning with trends like Hebbia’s $130 million raise for AI document search in 2024.
Details of NewLimit’s Funding and Research
NewLimit Raises $130M, valuing the company at $810 million, to advance its epigenetic platform. The startup has identified three drug candidates that reprogram liver cells, a key step toward therapies for aging-related conditions. NewLimit plans to initiate clinical trials by 2028, using AI to analyze cellular data and accelerate drug discovery. The funding will expand its team of 50 and enhance lab facilities in San Francisco.
Kleiner Perkins’ lead investment, joined by Joshua Kushner and Nat Friedman, underscores confidence in NewLimit’s approach. Unlike Calico Labs, which focuses on broad aging research, NewLimit targets specific cellular mechanisms, aiming for faster clinical outcomes. NewLimit obtains $130M to bridge biotech and AI, competing with firms like Skild AI, which raised $300 million in 2024.
Implications for the Biotech Market
NewLimit advances longevity research, potentially reshaping the biotech sector. Success in epigenetic reprogramming could lead to therapies for diseases like Alzheimer’s or heart disease, with the longevity market projected to reach $600 billion by 2030. NewLimit’s AI approach may reduce drug development costs, attracting investors seeking high-growth biotech opportunities. However, the long path to clinical trials poses risks, as seen in Calico’s slow progress since 2013.
Investor enthusiasm on X highlights NewLimit’s promise, but some caution against overhyping early-stage biotech. NewLimit secures $130M to drive innovation, positioning it as a leader in the anti-aging space alongside Altos Labs.
Opportunities for Investors and Researchers
NewLimit Raises $130M, creating opportunities for investors and researchers. Investors can explore biotech funds or startups like NewLimit, which align with AI and healthcare trends. The company’s $810 million valuation suggests strong growth potential, similar to Hebbia’s $700 million valuation in 2024. Researchers can join NewLimit’s team to work on epigenetic therapies, leveraging AI tools to accelerate discoveries.

NewLimit obtains $130M to fund partnerships with pharma firms, potentially licensing its drug candidates. Brian Armstrong’s Coinbase success adds credibility, attracting venture capital to longevity ventures.
Challenges Facing NewLimit’s Mission
Despite progress, NewLimit faces challenges. Epigenetic reprogramming is unproven in humans, with clinical trials years away, risking investor fatigue. Regulatory hurdles, including FDA scrutiny of AI-driven therapies, could delay approvals, as seen in biotech setbacks in 2024. Competition from Altos Labs and Calico Labs, backed by Google, adds pressure.
Market skepticism on X notes the high failure rate of longevity startups, emphasizing the need for rigorous testing. NewLimit must navigate these risks to deliver on its anti-aging promise.
Looking Ahead for NewLimit Raises $130M
As NewLimit advances longevity research, NewLimit Raises $130M to pave the way for clinical trials. Investors should monitor biotech trends, while researchers explore epigenetic opportunities. With AI and healthcare converging, NewLimit secures $130M to shape the future of anti-aging therapies.